Ayres, James, Ashford, Matthew, Stockl, Yannick, Prudhomme, Vassili, Ling, Kenneth B., Platts, James ORCID: https://orcid.org/0000-0002-1008-6595 and Morrill, Louis ORCID: https://orcid.org/0000-0002-6453-7531 2017. Deoxycyanamidation of alcohols with N-Cyano-N-phenyl-p-methylbenzenesulfonamide (NCTS). Organic Letters 19 (14) , pp. 3835-3838. 10.1021/acs.orglett.7b01710 |
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Official URL: http://doi.org/10.1021/acs.orglett.7b01710
Abstract
The first one-pot deoxycyanamidation of alcohols has been developed using N-cyano-N-phenyl-p-methylbenzenesulfonamide (NCTS) as both a sulfonyl transfer reagent and a cyanamide source, accessing a diverse range of tertiary cyanamides in excellent isolated yields. This approach exploits the underdeveloped desulfonylative (N–S bond cleavage) reactivity pathway of NCTS, which is more commonly employed for electrophilic C- and N-cyanation processes.
Item Type: | Article |
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Date Type: | Publication |
Status: | Published |
Schools: | Chemistry |
Subjects: | Q Science > QD Chemistry |
Publisher: | American Chemical Society |
ISSN: | 1523-7060 |
Funders: | EPSRC, DAAD |
Date of First Compliant Deposit: | 19 July 2017 |
Date of Acceptance: | 29 June 2017 |
Last Modified: | 04 May 2023 23:24 |
URI: | https://orca.cardiff.ac.uk/id/eprint/101944 |
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