A new droplet-forming fluidic junction for the generation of highly compartmentalised capsules

Li, J. ORCID: https://orcid.org/0000-0002-4672-6806 and Barrow, D. A. ORCID: https://orcid.org/0000-0003-2096-7262 2017. A new droplet-forming fluidic junction for the generation of highly compartmentalised capsules. Lab on a Chip 17 (16) , pp. 2873-2881. 10.1039/c7lc00618g

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Abstract

A new oscillatory microfluidic junction is described, which enables the consistent formation of highly uniform and complex double emulsions, and is demonstrated for the encapsulation of four different reagents within the inner droplets (called cores) of the double emulsion droplets. Once the double emulsion droplets had attained a spherical form, the cores assumed specific 3D arrangements, the orchestration of which appeared to depend upon the specific emulsion morphology. Such double emulsion droplets were used as templates to produce highly compartmentalised microcapsules and multisomes. Based on these construct models, we numerically demonstrated a model chemical reaction sequence between and within the liquid cores. This work could provide a platform to perform space/time-dependent applications, such as programmed experiments, synthesis, and delivery systems.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Engineering
Subjects:	T Technology > TC Hydraulic engineering. Ocean engineering
Additional Information:	This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material.
Publisher:	Royal Society of Chemistry
ISSN:	1473-0197
Date of First Compliant Deposit:	26 July 2017
Date of Acceptance:	14 July 2017
Last Modified:	11 May 2023 05:01
URI:	https://orca.cardiff.ac.uk/id/eprint/103007

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