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Animal venoms/toxins and the complement system

Tambourgi, Denise V. and van den Berg, Carmen W. 2014. Animal venoms/toxins and the complement system. Molecular Immunology 61 (2) , pp. 153-162. 10.1016/j.molimm.2014.06.020

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Nature is a wealthy source of agents that have been shown to be beneficial to human health, but nature is also a rich source of potential dangerous health damaging compounds. This review will summarise and discuss the agents from the animal kingdom that have been shown to interact with the human complement (C) system. Most of these agents are toxins found in animal venoms and animal secretions. In addition to the mechanism of action of these toxins, their contribution to the field of complement, their role in human pathology and the potential benefit to the venomous animal itself will be discussed. Potential therapeutic applications will also be discussed.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Publisher: Elsevier
ISSN: 0161-5890
Date of Acceptance: 10 June 2014
Last Modified: 13 Aug 2018 10:45

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