Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Effects of inhibitors on mitochondrial adenosine triphosphatase of Crithidia fasciculata: an unusual pattern of specificities

Yarlett, Nigel and Lloyd, David ORCID: https://orcid.org/0000-0002-5656-0571 1981. Effects of inhibitors on mitochondrial adenosine triphosphatase of Crithidia fasciculata: an unusual pattern of specificities. Molecular and Biochemical Parasitology 3 (1) , 13--17. 10.1016/0166-6851(81)90073-6

Full text not available from this repository.

Abstract

The mitochondrial adenosine triphosphatase of the kinetoplastid protozoon, Crithidia fasciculata, is inhibited by oligomycin, venturicidin, triethyltin sulphate, N,N′-dicyclohexylcarbodiimide, leucinostatin, Dio-9 and quercetin, but not by spegazzinine or by compounds which interact with the β- subunit of mitochondrial F1-ATPase (efrapeptin, aurovertin, citreoviridin or 4-chloro-7-nitrobenzofurazan). These results suggest that the F1 portion of the crithidial enzyme has an unusual type of β- subunit. Further evidence for the atypical nature of this enzyme is provided by the observation that F1-inhibitor proteins from Acanthamoeba castellanii or bovine heart mitochondria do not inhibit the C. fasciculata enzyme activity

Item Type: Article
Date Type: Publication
Status: Published
Schools: Biosciences
Publisher: Elsevier
ISSN: 0166-6851
Date of Acceptance: 10 September 1980
Last Modified: 26 Oct 2022 08:41
URI: https://orca.cardiff.ac.uk/id/eprint/128059

Citation Data

Cited 9 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item Edit Item