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GENMAP—A microbial genetics computer simulation

Day, M. J., Randerson, P. F. and Wood, A. J. 1985. GENMAP—A microbial genetics computer simulation. Journal of Biological Education 19 (1) , pp. 67-70. 10.1080/00219266.1985.9654689

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The design of an interactive computer program in microbial genetics is described. The program is divided into three stages: background information, questions, and the simulation. The results of simulated conjugation experiments with Escherichia coli allow eight chromosomal genes to be sequenced. These genes can be mapped relative to eight different sites of F plasmid insertion and transfer orientation. The simulation requires the student to choose appropriate donor and recipient strains of the bacterium, and to specify the constituents of selective media on which the progeny of each cross are grown. The simulation mimics the experimental errors which can affect the results and hence their interpretation. The value of this simulation is that it permits the student to work at his own pace and to develop an understanding of techniques for studying microbial genetics.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Biosciences
Publisher: Taylor & Francis (Routledge): SSH Titles
ISSN: 0021-9266
Last Modified: 19 Jun 2020 15:45

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